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An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human ß-Factor XIIa in a Cyclotide Scaffold.
Liu, Wenyu; de Veer, Simon J; Huang, Yen-Hua; Sengoku, Toru; Okada, Chikako; Ogata, Kazuhiro; Zdenek, Christina N; Fry, Bryan G; Swedberg, Joakim E; Passioura, Toby; Craik, David J; Suga, Hiroaki.
Afiliación
  • Liu W; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo, 113-0033, Japan.
  • de Veer SJ; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, Brisbane, QLD 4072, Australia.
  • Huang YH; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Sengoku T; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, Brisbane, QLD 4072, Australia.
  • Okada C; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Ogata K; Department of Biochemistry, Graduate School of Medicine, Yokohama City University, Yokohama, Kanagawa 236-0004, Japan.
  • Zdenek CN; Department of Biochemistry, Graduate School of Medicine, Yokohama City University, Yokohama, Kanagawa 236-0004, Japan.
  • Fry BG; Department of Biochemistry, Graduate School of Medicine, Yokohama City University, Yokohama, Kanagawa 236-0004, Japan.
  • Swedberg JE; Venom Evolution Lab, School of Biological Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Passioura T; Venom Evolution Lab, School of Biological Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Craik DJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Suga H; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo, 113-0033, Japan.
J Am Chem Soc ; 143(44): 18481-18489, 2021 11 10.
Article en En | MEDLINE | ID: mdl-34723512

Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas Sanguíneas / Factor XIIa / Ciclotidas Límite: Humans Idioma: En Revista: J Am Chem Soc Año: 2021 Tipo del documento: Article País de afiliación: Japón

Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas Sanguíneas / Factor XIIa / Ciclotidas Límite: Humans Idioma: En Revista: J Am Chem Soc Año: 2021 Tipo del documento: Article País de afiliación: Japón