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Dioscin: A review on pharmacological properties and therapeutic values.
Bandopadhyay, Shinjini; Anand, Uttpal; Gadekar, Vijaykumar Shivaji; Jha, Niraj Kumar; Gupta, Piyush Kumar; Behl, Tapan; Kumar, Manoj; Shekhawat, Mahipal S; Dey, Abhijit.
Afiliación
  • Bandopadhyay S; Amity Institute of Biotechnology, Amity University, Kolkata, West Bengal, India.
  • Anand U; Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
  • Gadekar VS; Zoology Department, Sangola College (affiliated to Punyashlok Ahilyadevi Holkar Solapur University), Solapur, Maharashtra, India.
  • Jha NK; Department of Biotechnology, School of Engineering & Technology, Sharda University, Greater Noida, Uttar Pradesh, India.
  • Gupta PK; Department of Life Sciences, School of Basic Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India.
  • Behl T; Department of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Chandigarh, Punjab, India.
  • Kumar M; Chemical and Biochemical Processing Division, ICAR - Central Institute for Research on Cotton Technology, Mumbai, Maharashtra, India.
  • Radha; School of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, India.
  • Shekhawat MS; Plant Biotechnology Unit, Kanchi Mamunivar Government Institute for Postgraduate Studies and Research, Puducherry, India.
  • Dey A; Department of Life Sciences, Presidency University, Kolkata, West Bengal, India.
Biofactors ; 48(1): 22-55, 2022 Jan.
Article en En | MEDLINE | ID: mdl-34919768
ABSTRACT
Dioscin has gained immense popularity as a natural, bioactive steroid saponin, which offers numerous medical benefits. The growing global incidence of disease-associated morbidity and mortality continues to compromise human health, facilitating an increasingly urgent need for nontoxic, noninvasive, and efficient treatment alternatives. Natural compounds can contribute vastly to this field. Over recent years, studies have demonstrated the remarkable protective actions of dioscin against a variety of human malignancies, metabolic disorders, organ injuries, and viral/fungal infections. The successful usage of this phytocompound has been widely seen in medical treatment procedures under traditional Chinese medicine, and it is becoming progressively prevalent worldwide. This review provides an insight into the wide spectrum of pharmacological activities of dioscin, as reported and compiled in recent literature. The various novel approaches and applications of dioscin also verify the advantages exhibited by plant extracts against commercially available drugs, highlighting the potential of phytochemical agents like dioscin to be further incorporated into clinical practice.
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Texto completo: 1 Colección: 01-internacional Asunto principal: Saponinas / Diosgenina / Neoplasias Límite: Humans Idioma: En Revista: Biofactors Asunto de la revista: BIOQUIMICA Año: 2022 Tipo del documento: Article País de afiliación: India

Texto completo: 1 Colección: 01-internacional Asunto principal: Saponinas / Diosgenina / Neoplasias Límite: Humans Idioma: En Revista: Biofactors Asunto de la revista: BIOQUIMICA Año: 2022 Tipo del documento: Article País de afiliación: India