Protein arginine methyltransferase 3 promotes glycolysis and hepatocellular carcinoma growth by enhancing arginine methylation of lactate dehydrogenase A.

Lei, Yu; Han, Ping; Chen, Yu; Wang, Han; Wang, Shuhui; Wang, Muru; Liu, Jingmei; Yan, Wei; Tian, Dean; Liu, Mei

Lei, Yu; Han, Ping; Chen, Yu; Wang, Han; Wang, Shuhui; Wang, Muru; Liu, Jingmei; Yan, Wei; Tian, Dean; Liu, Mei.

Afiliación

Lei Y; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Han P; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Chen Y; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Wang H; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Wang S; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Wang M; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Liu J; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Yan W; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Tian D; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Liu M; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.

Clin Transl Med ; 12(1): e686, 2022 01.

Article en En | MEDLINE | ID: mdl-35090076

Asunto(s)

Carcinoma Hepatocelular/tratamiento farmacológico; Glucólisis/efectos de los fármacos; L-Lactato Deshidrogenasa/farmacología; Proteína-Arginina N-Metiltransferasas/farmacología; Animales; Línea Celular Tumoral/efectos de los fármacos; Línea Celular Tumoral/metabolismo; Proliferación Celular/efectos de los fármacos; China; Modelos Animales de Enfermedad; Histología/instrumentación; Histología/tendencias; Humanos; L-Lactato Deshidrogenasa/metabolismo; Neoplasias Hepáticas/tratamiento farmacológico; Metilación/efectos de los fármacos; Ratones; Proteína-Arginina N-Metiltransferasas/metabolismo

Palabras clave

glycolysis; hepatocellular carcinoma (HCC); lactate dehydrogenase A (LDHA); protein arginine methyltransferase 3 (PRMT3)

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Texto completo: 1 Colección: 01-internacional Asunto principal: Proteína-Arginina N-Metiltransferasas / Carcinoma Hepatocelular / Glucólisis / L-Lactato Deshidrogenasa Límite: Animals / Humans País/Región como asunto: Asia Idioma: En Revista: Clin Transl Med Año: 2022 Tipo del documento: Article País de afiliación: China

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