A hypothetical proposal to employ meperidine and tamoxifen in treatment of glioblastoma. Role of P-glycoprotein, ceramide and metabolic pathways.

Altinoz, Meric A; Ozpinar, Alp; Hacker, Emily; Ozpinar, Aysel

Altinoz, Meric A; Ozpinar, Alp; Hacker, Emily; Ozpinar, Aysel.

Afiliación

Altinoz MA; Department of Biochemistry, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey; Department of Psychiatry, Maastricht University, Holland. Electronic address: maltinoz@gmail.com.
Ozpinar A; Department of Neurosurgery, Pittsburgh University, USA.
Hacker E; Department of Neurosurgery, Pittsburgh University, USA.
Ozpinar A; Department of Biochemistry, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.

Clin Neurol Neurosurg ; 215: 107208, 2022 04.

Article en En | MEDLINE | ID: mdl-35316699

Asunto(s)

Glioblastoma; Tamoxifeno; Miembro 1 de la Subfamilia B de Casetes de Unión a ATP/metabolismo; Apoptosis; Ceramidas/metabolismo; Ceramidas/farmacología; Ceramidas/uso terapéutico; Glioblastoma/tratamiento farmacológico; Humanos; Meperidina/farmacología; Redes y Vías Metabólicas; N-Metilaspartato/metabolismo; Tamoxifeno/metabolismo; Tamoxifeno/farmacología; Tamoxifeno/uso terapéutico

Palabras clave

Ceramide; Meperidine; P-glycoprotein; Tamoxifen, glioblastoma

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Texto completo: 1 Colección: 01-internacional Asunto principal: Tamoxifeno / Glioblastoma Límite: Humans Idioma: En Revista: Clin Neurol Neurosurg Año: 2022 Tipo del documento: Article

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