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MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, Hamed; Flórez, Andrés F; Kreth, Sina; Brückner, Lena M; Yildiz, Umut; Gartlgruber, Moritz; Odoni, Dorett I; Poschet, Gernot; Garbowicz, Karolina; Shao, Chunxuan; Klein, Corinna; Meier, Jasmin; Zeisberger, Petra; Nadler-Holly, Michal; Ziehm, Matthias; Paul, Franziska; Burhenne, Jürgen; Bell, Emma; Shaikhkarami, Marjan; Würth, Roberto; Stainczyk, Sabine A; Wecht, Elisa M; Kreth, Jochen; Büttner, Michael; Ishaque, Naveed; Schlesner, Matthias; Nicke, Barbara; Stresemann, Carlo; Llamazares-Prada, María; Reiling, Jan H; Fischer, Matthias; Amit, Ido; Selbach, Matthias; Herrmann, Carl; Wölfl, Stefan; Henrich, Kai-Oliver; Höfer, Thomas; Trumpp, Andreas; Westermann, Frank.
Afiliación
  • Alborzinia H; Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Heidelberg, Germany. hamed.alborzy@gmail.com.
  • Flórez AF; Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany. hamed.alborzy@gmail.com.
  • Kreth S; Division of Stem Cells and Cancer German Cancer Research Center and Center for Molecular Biology of the University of Heidelberg Alliance, Heidelberg, Germany. hamed.alborzy@gmail.com.
  • Brückner LM; Division of Theoretical Systems Biology, German Cancer Research Center, Heidelberg, Germany.
  • Yildiz U; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.
  • Gartlgruber M; Hopp Children's Cancer Center, Heidelberg, Germany.
  • Odoni DI; Division of Neuroblastoma Genomics, German Cancer Research Center, Heidelberg, Germany.
  • Poschet G; Hopp Children's Cancer Center, Heidelberg, Germany.
  • Garbowicz K; Division of Neuroblastoma Genomics, German Cancer Research Center, Heidelberg, Germany.
  • Shao C; Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Heidelberg, Germany.
  • Klein C; Division of Stem Cells and Cancer German Cancer Research Center and Center for Molecular Biology of the University of Heidelberg Alliance, Heidelberg, Germany.
  • Meier J; Hopp Children's Cancer Center, Heidelberg, Germany.
  • Zeisberger P; Division of Neuroblastoma Genomics, German Cancer Research Center, Heidelberg, Germany.
  • Nadler-Holly M; Bioinformatics and Omics Data Analytics, German Cancer Research Center, Heidelberg, Germany.
  • Ziehm M; Biomedical Informatics, Data Mining and Data Analytics, Augsburg University, Augsburg, Germany.
  • Paul F; Metabolomics Core Technology Platform, University of Heidelberg, Heidelberg, Germany.
  • Burhenne J; Hopp Children's Cancer Center, Heidelberg, Germany.
  • Bell E; Division of Neuroblastoma Genomics, German Cancer Research Center, Heidelberg, Germany.
  • Shaikhkarami M; Division of Theoretical Systems Biology, German Cancer Research Center, Heidelberg, Germany.
  • Würth R; Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Heidelberg, Germany.
  • Stainczyk SA; Division of Stem Cells and Cancer German Cancer Research Center and Center for Molecular Biology of the University of Heidelberg Alliance, Heidelberg, Germany.
  • Wecht EM; Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Heidelberg, Germany.
  • Kreth J; Division of Stem Cells and Cancer German Cancer Research Center and Center for Molecular Biology of the University of Heidelberg Alliance, Heidelberg, Germany.
  • Büttner M; Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Heidelberg, Germany.
  • Ishaque N; Division of Stem Cells and Cancer German Cancer Research Center and Center for Molecular Biology of the University of Heidelberg Alliance, Heidelberg, Germany.
  • Schlesner M; Proteome Dynamics, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
  • Nicke B; Proteome Dynamics, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
  • Stresemann C; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Llamazares-Prada M; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.
  • Reiling JH; Hopp Children's Cancer Center, Heidelberg, Germany.
  • Fischer M; Division of Neuroblastoma Genomics, German Cancer Research Center, Heidelberg, Germany.
  • Amit I; Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany.
  • Selbach M; Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Heidelberg, Germany.
  • Herrmann C; Division of Stem Cells and Cancer German Cancer Research Center and Center for Molecular Biology of the University of Heidelberg Alliance, Heidelberg, Germany.
  • Wölfl S; Hopp Children's Cancer Center, Heidelberg, Germany.
  • Henrich KO; Division of Neuroblastoma Genomics, German Cancer Research Center, Heidelberg, Germany.
  • Höfer T; Hopp Children's Cancer Center, Heidelberg, Germany.
  • Trumpp A; Division of Neuroblastoma Genomics, German Cancer Research Center, Heidelberg, Germany.
  • Westermann F; Hopp Children's Cancer Center, Heidelberg, Germany.
Nat Cancer ; 3(4): 471-485, 2022 04.
Article en En | MEDLINE | ID: mdl-35484422
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Texto completo: 1 Colección: 01-internacional Asunto principal: Ferroptosis / Neuroblastoma Tipo de estudio: Prognostic_studies Límite: Child / Humans Idioma: En Revista: Nat Cancer Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Asunto principal: Ferroptosis / Neuroblastoma Tipo de estudio: Prognostic_studies Límite: Child / Humans Idioma: En Revista: Nat Cancer Año: 2022 Tipo del documento: Article País de afiliación: Alemania