Gasdermin D mediates doxorubicin-induced cardiomyocyte pyroptosis and cardiotoxicity via directly binding to doxorubicin and changes in mitochondrial damage.

Ye, Bozhi; Shi, Xiaowen; Xu, Jianjiang; Dai, Shanshan; Xu, Jiajun; Fan, Xiaoxi; Han, Bingjiang; Han, Jibo

Ye, Bozhi; Shi, Xiaowen; Xu, Jianjiang; Dai, Shanshan; Xu, Jiajun; Fan, Xiaoxi; Han, Bingjiang; Han, Jibo.

Afiliación

Ye B; Department of Cardiology, The First Affiliated Hospital of WenZhou Medical University, WenZhou, Zhejiang 325000, China.
Shi X; Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, China.
Xu J; Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, China.
Dai S; Department of Cardiology, The First Affiliated Hospital of WenZhou Medical University, WenZhou, Zhejiang 325000, China.
Xu J; Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, China.
Fan X; Department of Cardiology, The First Affiliated Hospital of WenZhou Medical University, WenZhou, Zhejiang 325000, China.
Han B; Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, China.
Han J; Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, China. Electronic address: jibohanjx2y@163.com.

Transl Res ; 248: 36-50, 2022 10.

Article en En | MEDLINE | ID: mdl-35545198

Asunto(s)

Cardiotoxicidad; Piroptosis; Animales; Doxorrubicina; Ratones; Miocitos Cardíacos

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Texto completo: 1 Colección: 01-internacional Asunto principal: Cardiotoxicidad / Piroptosis Límite: Animals Idioma: En Revista: Transl Res Asunto de la revista: MEDICINA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2022 Tipo del documento: Article País de afiliación: China

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