LXRß Activation Inhibits the Proliferation of Small-cell Lung Cancer Cells by Depleting Cellular Cholesterol.

Kashiwagi, Korehito; Sato-Yazawa, Hanako; Ishii, Jun; Kohno, Kakeru; Tatsuta, Isaaki; Miyazawa, Tadasuke; Takagi, Megumi; Chiba, Hideki; Yazawa, Takuya

Kashiwagi, Korehito; Sato-Yazawa, Hanako; Ishii, Jun; Kohno, Kakeru; Tatsuta, Isaaki; Miyazawa, Tadasuke; Takagi, Megumi; Chiba, Hideki; Yazawa, Takuya.

Afiliación

Kashiwagi K; Department of Pathology, Dokkyo Medical University School of Medicine and Graduate School of Medicine, Mibu, Japan; k-kore@dokkyomed.ac.jp.
Sato-Yazawa H; Department of Pathology, Dokkyo Medical University School of Medicine and Graduate School of Medicine, Mibu, Japan.
Ishii J; Department of Pathology, Dokkyo Medical University School of Medicine and Graduate School of Medicine, Mibu, Japan.
Kohno K; Department of Pathology, Dokkyo Medical University School of Medicine and Graduate School of Medicine, Mibu, Japan.
Tatsuta I; Institute of Life Innovation Studies, Toyo University, Itakura-machi, Japan.
Miyazawa T; Department of Pathology, Dokkyo Medical University School of Medicine and Graduate School of Medicine, Mibu, Japan.
Takagi M; Department of Pathology, Dokkyo Medical University School of Medicine and Graduate School of Medicine, Mibu, Japan.
Chiba H; Department of Pathology, Dokkyo Medical University School of Medicine and Graduate School of Medicine, Mibu, Japan.
Yazawa T; Department of Basic Pathology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Anticancer Res ; 42(6): 2923-2930, 2022 Jun.

Article en En | MEDLINE | ID: mdl-35641269

Asunto(s)

Neoplasias Pulmonares; Receptores Nucleares Huérfanos; Proliferación Celular; Colesterol/metabolismo; Humanos; Hidrocarburos Fluorados/farmacología; Receptores X del Hígado/genética; Neoplasias Pulmonares/tratamiento farmacológico; Neoplasias Pulmonares/genética; Receptores Nucleares Huérfanos/genética; Receptores Nucleares Huérfanos/metabolismo; Sulfonamidas/farmacología

Palabras clave

ABCA1; Liver X receptors; T0901317; cholesterol metabolism; small-cell lung cancer

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Texto completo: 1 Colección: 01-internacional Asunto principal: Receptores Nucleares Huérfanos / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Anticancer Res Año: 2022 Tipo del documento: Article

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