Folic acid ameliorates N-methyl-N'-nitro-N-nitrosoguanidine-induced esophageal inflammation via modulation of the NF-&#954;B pathway.

Cheng, Suizhi; Che, Li; Yang, Qingqing; Sun, Rongjing; Nie, Yuhong; Shi, Haoyue; Ding, Yiwen; Wang, Li; Du, Zuo; Liu, Zhenzhong

Folic acid ameliorates N-methyl-N'-nitro-N-nitrosoguanidine-induced esophageal inflammation via modulation of the NF-κB pathway.

Cheng, Suizhi; Che, Li; Yang, Qingqing; Sun, Rongjing; Nie, Yuhong; Shi, Haoyue; Ding, Yiwen; Wang, Li; Du, Zuo; Liu, Zhenzhong.

Afiliación

Cheng S; School of Public Health, North Sichuan Medical College, Nanchong 637000, China; School of Pharmacy, North Sichuan Medical College, Nanchong 637000, China.
Che L; School of Public Health, North Sichuan Medical College, Nanchong 637000, China.
Yang Q; School of Public Health, North Sichuan Medical College, Nanchong 637000, China.
Sun R; School of Public Health, North Sichuan Medical College, Nanchong 637000, China.
Nie Y; School of Public Health, North Sichuan Medical College, Nanchong 637000, China.
Shi H; School of Public Health, North Sichuan Medical College, Nanchong 637000, China.
Ding Y; School of Public Health, North Sichuan Medical College, Nanchong 637000, China.
Wang L; School of Public Health, North Sichuan Medical College, Nanchong 637000, China; School of Pharmacy, North Sichuan Medical College, Nanchong 637000, China.
Du Z; School of Public Health, North Sichuan Medical College, Nanchong 637000, China.
Liu Z; School of Public Health, North Sichuan Medical College, Nanchong 637000, China; Innovative Platform of Basic Medical Sciences, School of Basic Medical Sciences, North Sichuan Medical College, Nanchong 637000, China. Electronic address: liuzhenzhong@nsmc.edu.cn.

Toxicol Appl Pharmacol ; 447: 116087, 2022 07 15.

Article en En | MEDLINE | ID: mdl-35643124

Asunto(s)

Metilnitronitrosoguanidina; FN-kappa B; Animales; Ácido Fólico/farmacología; Ácido Fólico/uso terapéutico; Inflamación/inducido químicamente; Inflamación/tratamiento farmacológico; Inflamación/prevención & control; Interleucina-6; Interleucina-8; Metilnitronitrosoguanidina/toxicidad; Inhibidor NF-kappaB alfa; FN-kappa B/metabolismo; Ratas; Ratas Sprague-Dawley; Factor de Necrosis Tumoral alfa

Palabras clave

Esophagus; Folic acid; Inflammation; MNNG; Nuclear factor-κB

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Texto completo: 1 Colección: 01-internacional Asunto principal: FN-kappa B / Metilnitronitrosoguanidina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: China

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