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Whole-genome CRISPR screening identifies N-glycosylation as a genetic and therapeutic vulnerability in CALR-mutant MPNs.
Jutzi, Jonas S; Marneth, Anna E; Ciboddo, Michele; Guerra-Moreno, Angel; Jiménez-Santos, María José; Kosmidou, Anastasia; Dressman, James W; Liang, Hongyan; Hamel, Rebecca; Lozano, Patricia; Rumi, Elisa; Doench, John G; Gotlib, Jason; Krishnan, Anandi; Elf, Shannon; Al-Shahrour, Fátima; Mullally, Ann.
Afiliación
  • Jutzi JS; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Marneth AE; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Ciboddo M; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Guerra-Moreno A; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
  • Jiménez-Santos MJ; The Ben May Department for Cancer Research, University of Chicago, Chicago, IL.
  • Kosmidou A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Dressman JW; Bioinformatics Unit, Structural Biology Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Liang H; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Hamel R; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
  • Lozano P; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC.
  • Rumi E; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC.
  • Doench JG; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Gotlib J; RWTH Aachen University, Aachen, Germany.
  • Krishnan A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Elf S; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
  • Al-Shahrour F; Hematology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia, Italy.
  • Mullally A; Broad Institute, Cambridge, MA.
Blood ; 140(11): 1291-1304, 2022 09 15.
Article en En | MEDLINE | ID: mdl-35763665
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Texto completo: 1 Colección: 01-internacional Asunto principal: Calreticulina / Trastornos Mieloproliferativos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Blood Año: 2022 Tipo del documento: Article País de afiliación: Marruecos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Asunto principal: Calreticulina / Trastornos Mieloproliferativos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Blood Año: 2022 Tipo del documento: Article País de afiliación: Marruecos