IMP075 targeting ClpP for colon cancer therapy in vivo and in vitro.

Zhang, Jiangnan; Luo, Baozhu; Sui, Jing; Qiu, Zhiqiang; Huang, Jiasheng; Yang, Tao; Luo, Youfu

Zhang, Jiangnan; Luo, Baozhu; Sui, Jing; Qiu, Zhiqiang; Huang, Jiasheng; Yang, Tao; Luo, Youfu.

Afiliación

Zhang J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Luo B; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Sui J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Qiu Z; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Huang J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Yang T; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China; Institute of Immunology and Inflammation, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic a
Luo Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address: luo_youfu@scu.edu.cn.

Biochem Pharmacol ; 204: 115232, 2022 10.

Article en En | MEDLINE | ID: mdl-36030831

Asunto(s)

Neoplasias del Colon; Péptido Hidrolasas; Animales; Línea Celular Tumoral; Neoplasias del Colon/tratamiento farmacológico; Endopeptidasa Clp/genética; Endopeptidasa Clp/metabolismo; Humanos; Ratones; Péptido Hidrolasas/uso terapéutico; ARN Interferente Pequeño; Sincalida/uso terapéutico

Palabras clave

ASLAN003 (PubChem CID: 24986824); Activator; Bortezomib (PubChem CID: 387447); Caseinolytic protease P; Colorectal cancer; Linezolid (PubChem CID: 441401); Mitochondria; ONC201; ONC201 (PubChem CID: 73777259); Pifithrin-µ (PubChem CID: 327653); Targeted drugs

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Texto completo: 1 Colección: 01-internacional Asunto principal: Péptido Hidrolasas / Neoplasias del Colon Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Biochem Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: China

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