Different Inhibition of Nrf2 by Two Keap1 Isoforms &#945; and ß to Shape Malignant Behaviour of Human Hepatocellular Carcinoma.

Chen, Feilong; Xiao, Mei; Feng, Jing; Wufur, Reziyamu; Liu, Keli; Hu, Shaofan; Zhang, Yiguo

Different Inhibition of Nrf2 by Two Keap1 Isoforms α and ß to Shape Malignant Behaviour of Human Hepatocellular Carcinoma.

Chen, Feilong; Xiao, Mei; Feng, Jing; Wufur, Reziyamu; Liu, Keli; Hu, Shaofan; Zhang, Yiguo.

Afiliación

Chen F; College of Bioengineering, Graduate School, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.
Xiao M; Chongqing University Jiangjin Hospital, School of Medicine, Chongqing University, No. 725 Jiangzhou Avenue, Dingshan Street, Jiangjin District, Chongqing 402260, China.
Feng J; The Laboratory of Cell Biochemistry and Topogenetic Regulation, College of Bioengineering, Faculty of Medical Sciences, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.
Wufur R; College of Bioengineering, Graduate School, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.
Liu K; The Laboratory of Cell Biochemistry and Topogenetic Regulation, College of Bioengineering, Faculty of Medical Sciences, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.
Hu S; College of Bioengineering, Graduate School, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.
Zhang Y; Chongqing University Jiangjin Hospital, School of Medicine, Chongqing University, No. 725 Jiangzhou Avenue, Dingshan Street, Jiangjin District, Chongqing 402260, China.

Int J Mol Sci ; 23(18)2022 Sep 07.

Article en En | MEDLINE | ID: mdl-36142252

Asunto(s)

Carcinoma Hepatocelular; Neoplasias Hepáticas; Factor 2 Relacionado con NF-E2; Animales; Humanos; Ratones; Antioxidantes/farmacología; Carcinoma Hepatocelular/genética; Proteína 1 Asociada A ECH Tipo Kelch/genética; Proteína 1 Asociada A ECH Tipo Kelch/metabolismo; Neoplasias Hepáticas/genética; Ratones Desnudos; Factor 2 Relacionado con NF-E2/metabolismo; Estrés Oxidativo; Fosfatidilinositol 3-Quinasas/metabolismo; Isoformas de Proteínas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Serina-Treonina Quinasas TOR/metabolismo

Palabras clave

EMT; HO-1; Keap1; Keap1α; Keap1ß; Nrf2; PI3K; PTEN; mTOR

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Texto completo: 1 Colección: 01-internacional Asunto principal: Carcinoma Hepatocelular / Factor 2 Relacionado con NF-E2 / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: China

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