Mortality Associated With Occupational Exposure in Helsinki, Finland-A 24-Year Follow-up.
J Occup Environ Med
; 65(1): 22-28, 2023 01 01.
Article
en En
| MEDLINE
| ID: mdl-36200674
ABSTRACT
OBJECTIVES:
Our objective was to study mortality related to different obstructive lung diseases, occupational exposure, and their potential joint effect in a large, randomized population-based cohort.METHODS:
We divided the participants based on the answers to asthma and chronic obstructive pulmonary disease (COPD) diagnoses and occupational exposure and used a combined effects model and compared the results to no asthma or COPD with no occupational exposure.RESULTS:
High exposure had a hazards ratio (HR) of 1.34 (1.11-1.62) and asthma and COPD coexistence of 1.58 (1.10-2.27). The combined effects of intermediate exposure and coexistence had an HR of 2.20 (1.18-4.09), high exposure with coexistence of 1.94 (1.10-3.42) for overall mortality, and sub-HR for respiratory-related mortality of 3.21 (1.87-5.50).CONCLUSIONS:
High occupational exposure increased overall but not respiratory-related mortality hazards, while coexisting asthma and COPD overall and respiratory-related hazards of mortality.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Asma
/
Exposición Profesional
/
Enfermedad Pulmonar Obstructiva Crónica
Tipo de estudio:
Clinical_trials
/
Risk_factors_studies
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Occup Environ Med
Asunto de la revista:
MEDICINA OCUPACIONAL
/
SAUDE AMBIENTAL
Año:
2023
Tipo del documento:
Article