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Tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine: An open-label partially-randomised ascending dose phase I trial.
Madhavan, Meera; Ritchie, Adam J; Aboagye, Jeremy; Jenkin, Daniel; Provstgaad-Morys, Samuel; Tarbet, Iona; Woods, Danielle; Davies, Sophie; Baker, Megan; Platt, Abigail; Flaxman, Amy; Smith, Holly; Belij-Rammerstorfer, Sandra; Wilkins, Deidre; Kelly, Elizabeth J; Villafana, Tonya; Green, Justin A; Poulton, Ian; Lambe, Teresa; Hill, Adrian V S; Ewer, Katie J; Douglas, Alexander D.
Afiliación
  • Madhavan M; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LE, UK.
  • Ritchie AJ; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Aboagye J; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Jenkin D; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LE, UK.
  • Provstgaad-Morys S; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Tarbet I; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Woods D; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Davies S; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Baker M; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LE, UK.
  • Platt A; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LE, UK.
  • Flaxman A; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Smith H; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Belij-Rammerstorfer S; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Wilkins D; Translational Medicine, Vaccines & Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, 1 Medimmune Way, Gaithersburg, MD 20878, USA.
  • Kelly EJ; Translational Medicine, Vaccines & Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, 1 Medimmune Way, Gaithersburg, MD 20878, USA.
  • Villafana T; Clinical Development, Vaccines & Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.
  • Green JA; Clinical Development, Vaccines & Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Poulton I; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LE, UK.
  • Lambe T; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK; Oxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LE, UK; China Academy of Medical Sciences Oxford Institute, University of
  • Hill AVS; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Ewer KJ; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK.
  • Douglas AD; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7BN, UK. Electronic address: sandy.douglas@ndm.ox.ac.uk.
EBioMedicine ; 85: 104298, 2022 Nov.
Article en En | MEDLINE | ID: mdl-36229342
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Texto completo: 1 Colección: 01-internacional Asunto principal: Vacunas Virales / COVID-19 Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Humans Idioma: En Revista: EBioMedicine Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Asunto principal: Vacunas Virales / COVID-19 Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Humans Idioma: En Revista: EBioMedicine Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido