Second window ICG predicts postoperative MRI gadolinium enhancement in high grade gliomas and brain metastases.
Neurosurg Focus Video
; 6(1): V8, 2022 Jan.
Article
en En
| MEDLINE
| ID: mdl-36284582
ABSTRACT
A prospective trial evaluating the utility of second window indocyanine green (SWIG) in predicting postoperative MRI gadolinium enhancement was performed on high-grade gliomas (HGGs) and brain metastases. Compared to white light alone, SWIG demonstrated a higher sensitivity, negative predictive value, and accuracy in predicting residual neoplasm on MRI. The specificity of SWIG for predicting MRI enhancement was higher in HGGs than brain metastases. Clinically, near-infrared (NIR) imaging was better able to predict tumor recurrence than postoperative MRI. These results illustrate how SWIG is able to take advantage of gadolinium-like distribution properties to extravasate into the tumor microenvironment, enabling guidance in surgical resection. The video can be found here https//stream.cadmore.media/r10.3171/2021.10.FOCVID21204.
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1
Colección:
01-internacional
Tipo de estudio:
Guideline
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Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
Neurosurg Focus Video
Año:
2022
Tipo del documento:
Article