Low Dose Berberine Suppresses Cholangiocarcinoma Cell Progression as a Multi-Kinase Inhibitor.

Obchoei, Sumalee; Detarya, Marutpong; Boonnate, Piyanard; Saranaruk, Paksiree; Vaeteewoottacharn, Kulthida; Mahalapbutr, Panupong; Okada, Seiji; Wongkham, Sopit

Obchoei, Sumalee; Detarya, Marutpong; Boonnate, Piyanard; Saranaruk, Paksiree; Vaeteewoottacharn, Kulthida; Mahalapbutr, Panupong; Okada, Seiji; Wongkham, Sopit.

Afiliación

Obchoei S; Division of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Songkhla 90110, Thailand.
Detarya M; Department of Biochemistry, Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Boonnate P; Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen 40002, Thailand.
Saranaruk P; Division of Hematopoiesis, Joint Research Center for Human Retrovirus Infection and Graduate School of Medical Sciences, Kumamoto University, Kumamoto, 860-0811 Japan.
Vaeteewoottacharn K; Department of Biochemistry, Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Mahalapbutr P; Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen 40002, Thailand.
Okada S; Department of Biochemistry, Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Wongkham S; Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen 40002, Thailand.

Asian Pac J Cancer Prev ; 23(10): 3379-3386, 2022 Oct 01.

Article en En | MEDLINE | ID: mdl-36308362

Asunto(s)

Antineoplásicos; Berberina; Neoplasias de los Conductos Biliares; Colangiocarcinoma; Humanos; Neoplasias de los Conductos Biliares/patología; Berberina/farmacología; Proteínas Proto-Oncogénicas c-akt/metabolismo; Factor de Crecimiento Epidérmico/metabolismo; Factor de Crecimiento Epidérmico/farmacología; Factor de Crecimiento Epidérmico/uso terapéutico; Simulación del Acoplamiento Molecular; Línea Celular Tumoral; Colangiocarcinoma/patología; Movimiento Celular; Proliferación Celular; Antineoplásicos/farmacología; Antineoplásicos/uso terapéutico; Conductos Biliares Intrahepáticos/patología; Receptores ErbB/metabolismo

Palabras clave

Benzylisoquinoline alkaloid; Bile duct cancer; EGFR; VEGFA; epithelial-mesenchymal transition

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Texto completo: 1 Colección: 01-internacional Asunto principal: Berberina / Neoplasias de los Conductos Biliares / Colangiocarcinoma / Antineoplásicos Límite: Humans Idioma: En Revista: Asian Pac J Cancer Prev Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: Tailandia

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