Extracellular Vesicles as Biomarkers and Therapeutics for Inflammatory Eye Diseases.
Mol Pharm
; 20(1): 23-40, 2023 01 02.
Article
en En
| MEDLINE
| ID: mdl-36332193
ABSTRACT
Extracellular vesicles (EVs) are a group of cell-derived membrane vesicles of varying sizes that can be secreted by most cells. Depending on the type of cell they are derived from, EVs may contain a variety of cargo including proteins, lipids, miRNA, and DNA. Functionally, EVs play important roles in physiological and pathological processes through intercellular communication. While there has already been significant literature on the involvement of EVs in neurological and cardiovascular disease as well as cancer, recent evidence suggests that EVs may also play a role in mediating inflammatory eye diseases. This paper summarizes current advancements in ocular EV research as well as new ways by which EVs may be utilized as novel biomarkers of or therapeutics for inflammatory eye diseases.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
MicroARNs
/
Oftalmopatías
/
Vesículas Extracelulares
/
Neoplasias
Límite:
Humans
Idioma:
En
Revista:
Mol Pharm
Asunto de la revista:
BIOLOGIA MOLECULAR
/
FARMACIA
/
FARMACOLOGIA
Año:
2023
Tipo del documento:
Article
País de afiliación:
Nueva Zelanda