Screening Method for the Identification of Compounds That Activate Pregnane X Receptor.

Lynch, Caitlin; Sakamuru, Srilatha; Xia, Menghang

Lynch, Caitlin; Sakamuru, Srilatha; Xia, Menghang.

Afiliación

Lynch C; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA.
Sakamuru S; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA.
Xia M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA.

Curr Protoc ; 2(12): e615, 2022 Dec.

Article en En | MEDLINE | ID: mdl-36469580

Asunto(s)

Citocromo P-450 CYP3A; Receptores de Esteroides; Humanos; Receptor X de Pregnano/genética; Citocromo P-450 CYP3A/genética; Receptores de Esteroides/genética; Receptores Citoplasmáticos y Nucleares; Luciferasas/metabolismo

Palabras clave

PXR reporter gene assay; pregnane X receptor; quantitative high-throughput screening

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Texto completo: 1 Colección: 01-internacional Asunto principal: Receptores de Esteroides / Citocromo P-450 CYP3A Tipo de estudio: Diagnostic_studies / Guideline / Screening_studies Límite: Humans Idioma: En Revista: Curr Protoc Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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