Cardiac glycoside neriifolin exerts anti-cancer activity in prostate cancer cells by attenuating DNA damage repair through endoplasmic reticulum stress.

Zhao, Wanlu; Li, Guihuan; Zhang, Qianbing; Chen, Meixuan; He, Lijun; Wu, Zhicong; Zhang, Yihe; Fan, Mingming; Liang, Yanling; Zhang, Wenlong; Zeng, Fangyin; Deng, Fan

Zhao, Wanlu; Li, Guihuan; Zhang, Qianbing; Chen, Meixuan; He, Lijun; Wu, Zhicong; Zhang, Yihe; Fan, Mingming; Liang, Yanling; Zhang, Wenlong; Zeng, Fangyin; Deng, Fan.

Afiliación

Zhao W; Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Li G; Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Zhang Q; Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Chen M; Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
He L; Department of Nursing, Nanfang Hospital, Southern Medical University, Guangzhou 501515, China.
Wu Z; Department of Clinical Laboratory, Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Zhang Y; Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Fan M; Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Liang Y; Department of Clinical Laboratory, Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Zhang W; Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Zeng F; Department of Clinical Laboratory, Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China. Electronic address: zengfy@126.com.
Deng F; Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China. Electronic address: fandeng@smu.edu.cn.

Biochem Pharmacol ; 209: 115453, 2023 03.

Article en En | MEDLINE | ID: mdl-36792037

Asunto(s)

Glicósidos Cardíacos; Neoplasias de la Próstata; Humanos; Masculino; Animales; Ratones; Antagonistas de Andrógenos; Ratones Desnudos; eIF-2 Quinasa/genética; Estrés del Retículo Endoplásmico/fisiología; Apoptosis; Daño del ADN; Factor de Transcripción CHOP/metabolismo

Palabras clave

Apoptosis; Cardiac glycoside; DNA damage repair; Endoplasmic reticulum stress; Neriifolin; Prostate cancer

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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias de la Próstata / Glicósidos Cardíacos Límite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: China

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