The effects of computerised cognitive training on post-CABG delirium and cognitive change: A prospective randomised controlled trial.
Delirium (Bielef)
; 1: 67976, 2023 Feb 21.
Article
en En
| MEDLINE
| ID: mdl-36936538
ABSTRACT
Background:
Cognitive impairments, including delirium, are common after coronary artery bypass grafting (CABG). Improving cognition pre- and post-operatively using computerised cognitive training (CCT) may be an effective approach to improve cognitive outcomes in CABG patients.Objectives:
Investigate the effect of remotely supervised CCT on cognitive outcomes, including delirium, in older adults undergoing CABG surgery.Methods:
Thirty-six participants, were analysed in a single-blinded randomised controlled trial (CCT Intervention n = 18, Control n = 18). CCT was completed by the intervention group pre-operatively (every other day, 45-60-minute sessions until surgery) and post-operatively, beginning 1-month post-CABG (3 x 45-60-minute sessions/week for 12-weeks), while the control group maintained usual care plus weekly phone calls. Cognitive assessments were conducted pre- and post-operatively at multiple follow-ups (discharge, 4-months and 6-months). Post-operative delirium incidence was assessed daily until discharge. Cognitive change data were calculated at each follow-up for each cognitive test (Addenbrooke's Cognitive Examination III and CANTAB; z-scored).Results:
Adherence to the CCT intervention (completion of three pre-operative or 66% of post-operative sessions) was achieved in 68% of pre-CABG and 59% of post-CABG participants. There were no statistically significant effects of CCT on any cognitive outcome, including delirium incidence.Conclusion:
Adherence to the CCT program was comparatively higher than previous feasibility studies, possibly due to the level of supervision and support provided (blend of face-to-face and home-based training, with support phone calls). Implementing CCT interventions both pre- and post-operatively is feasible in those undergoing CABG. No statistically significant benefits from the CCT interventions were identified for delirium or cognitive function post-CABG, likely due to the sample size available (study recruitment greatly impacted by COVID-19). It also may be the case that multimodal intervention would be more effective.
Texto completo:
1
Colección:
01-internacional
Tipo de estudio:
Clinical_trials
/
Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
Delirium (Bielef)
Año:
2023
Tipo del documento:
Article