Age-related loss of chromosome Y is associated with levels of sex hormone binding globulin and clonal hematopoiesis defined by TET2, TP53, and CBL mutations.

Dawoud, Ahmed A Z; Tapper, William J; Cross, Nicholas C P

Age-related loss of chromosome Y is associated with levels of sex hormone binding globulin and clonal hematopoiesis defined by TET2, TP53, and CBL mutations.

Dawoud, Ahmed A Z; Tapper, William J; Cross, Nicholas C P.

Afiliación

Dawoud AAZ; School of Medicine, University of Southampton, Southampton, Hampshire SO17 1BJ, UK.
Tapper WJ; Wessex Regional Genetics Laboratory, Salisbury NHS Foundation Trust, Salisbury, Wiltshire SP2 8BJ, UK.
Cross NCP; School of Medicine, University of Southampton, Southampton, Hampshire SO17 1BJ, UK.

Sci Adv ; 9(16): eade9746, 2023 04 21.

Article en En | MEDLINE | ID: mdl-37083525

Asunto(s)

Cromosomas Humanos Y; Dioxigenasas; Humanos; Masculino; Hematopoyesis Clonal; Dioxigenasas/genética; Proteínas de Unión al ADN/genética; Mosaicismo; Mutación; Globulina de Unión a Hormona Sexual/genética; Proteína p53 Supresora de Tumor/genética

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Texto completo: 1 Colección: 01-internacional Asunto principal: Cromosomas Humanos Y / Dioxigenasas Tipo de estudio: Clinical_trials / Prognostic_studies / Risk_factors_studies Límite: Humans / Male Idioma: En Revista: Sci Adv Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido

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