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THEMIS increases TCR signaling in CD4+CD8+ thymocytes by inhibiting the activity of the tyrosine phosphatase SHP1.
Choi, Seeyoung; Lee, Jan; Hatzihristidis, Teri; Gaud, Guillaume; Dutta, Avik; Arya, Awadhesh; Clubb, Lauren M; Stamos, Daniel B; Markovics, Adrienn; Mikecz, Katalin; Love, Paul E.
Afiliación
  • Choi S; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Lee J; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Hatzihristidis T; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Gaud G; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Dutta A; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Arya A; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Clubb LM; Shock, Trauma and Anesthesiology Research (STAR) Center, University of Maryland, School of Medicine, Baltimore, MD 21201, USA.
  • Stamos DB; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Markovics A; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Mikecz K; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
  • Love PE; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
Sci Signal ; 16(784): eade1274, 2023 05 09.
Article en En | MEDLINE | ID: mdl-37159521
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Texto completo: 1 Colección: 01-internacional Asunto principal: Péptidos y Proteínas de Señalización Intercelular / Proteína Tirosina Fosfatasa no Receptora Tipo 6 / Timocitos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Péptidos y Proteínas de Señalización Intercelular / Proteína Tirosina Fosfatasa no Receptora Tipo 6 / Timocitos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos