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Deoxycholic Acid for Dercum Disease: Repurposing a Cosmetic Agent to Treat a Rare Disease.
Silence, Channi; Rice, Shauna M; Liteplo, Andrew; McFadden, Kathleen; Al Jalbout, Nour; Al Saud, Ahad Alhassan; Gao, Jennifer; Kourosh, Arianne S.
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  • Silence C; Ms. Silence, as well as Drs. Liteplo, McFadden, Al Jalbout, Al Saud, and Kourosh, are from the Massachusetts General Hospital, Boston. Ms. Silence and Dr. Kourosh are from the Department of Dermatology. Dr. Kourosh also is from the Harvard Medical School, Boston. Ms. Rice is from the University of M
  • Rice SM; Ms. Silence, as well as Drs. Liteplo, McFadden, Al Jalbout, Al Saud, and Kourosh, are from the Massachusetts General Hospital, Boston. Ms. Silence and Dr. Kourosh are from the Department of Dermatology. Dr. Kourosh also is from the Harvard Medical School, Boston. Ms. Rice is from the University of M
  • Liteplo A; Ms. Silence, as well as Drs. Liteplo, McFadden, Al Jalbout, Al Saud, and Kourosh, are from the Massachusetts General Hospital, Boston. Ms. Silence and Dr. Kourosh are from the Department of Dermatology. Dr. Kourosh also is from the Harvard Medical School, Boston. Ms. Rice is from the University of M
  • McFadden K; Ms. Silence, as well as Drs. Liteplo, McFadden, Al Jalbout, Al Saud, and Kourosh, are from the Massachusetts General Hospital, Boston. Ms. Silence and Dr. Kourosh are from the Department of Dermatology. Dr. Kourosh also is from the Harvard Medical School, Boston. Ms. Rice is from the University of M
  • Al Jalbout N; Ms. Silence, as well as Drs. Liteplo, McFadden, Al Jalbout, Al Saud, and Kourosh, are from the Massachusetts General Hospital, Boston. Ms. Silence and Dr. Kourosh are from the Department of Dermatology. Dr. Kourosh also is from the Harvard Medical School, Boston. Ms. Rice is from the University of M
  • Al Saud AA; Ms. Silence, as well as Drs. Liteplo, McFadden, Al Jalbout, Al Saud, and Kourosh, are from the Massachusetts General Hospital, Boston. Ms. Silence and Dr. Kourosh are from the Department of Dermatology. Dr. Kourosh also is from the Harvard Medical School, Boston. Ms. Rice is from the University of M
  • Gao J; Ms. Silence, as well as Drs. Liteplo, McFadden, Al Jalbout, Al Saud, and Kourosh, are from the Massachusetts General Hospital, Boston. Ms. Silence and Dr. Kourosh are from the Department of Dermatology. Dr. Kourosh also is from the Harvard Medical School, Boston. Ms. Rice is from the University of M
  • Kourosh AS; Ms. Silence, as well as Drs. Liteplo, McFadden, Al Jalbout, Al Saud, and Kourosh, are from the Massachusetts General Hospital, Boston. Ms. Silence and Dr. Kourosh are from the Department of Dermatology. Dr. Kourosh also is from the Harvard Medical School, Boston. Ms. Rice is from the University of M
Cutis ; 111(4): E4-E8, 2023 Apr.
Article en En | MEDLINE | ID: mdl-37289681
ABSTRACT
Dercum disease is a rare condition characterized by multiple painful fatty tumors distributed throughout the body. There currently are no US Food and Drug Administration-approved treatments for Dercum disease, and the treatments tried have shown little to no efficacy, leaving many patients with a profoundly negative impact on quality of life. We present a case series of 3 patients who were diagnosed with Dercum disease and were treated with deoxycholic acid (DCA), a therapy approved for adipolysis of submental fat. The patients experienced a reduction in tumor size with radiographic evidence as well as a notable reduction in symptoms.
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Texto completo: 1 Colección: 01-internacional Asunto principal: Adiposis Dolorosa / Técnicas Cosméticas / Lipoma Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Cutis Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Asunto principal: Adiposis Dolorosa / Técnicas Cosméticas / Lipoma Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Cutis Año: 2023 Tipo del documento: Article