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Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold.
Castells-Graells, Roger; Meador, Kyle; Arbing, Mark A; Sawaya, Michael R; Gee, Morgan; Cascio, Duilio; Gleave, Emma; Debreczeni, Judit É; Breed, Jason; Leopold, Karoline; Patel, Ankoor; Jahagirdar, Dushyant; Lyons, Bronwyn; Subramaniam, Sriram; Phillips, Chris; Yeates, Todd O.
Afiliación
  • Castells-Graells R; Department of Energy, Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095.
  • Meador K; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095.
  • Arbing MA; Department of Energy, Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095.
  • Sawaya MR; Department of Energy, Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095.
  • Gee M; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095.
  • Cascio D; Department of Energy, Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095.
  • Gleave E; Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, United Kingdom.
  • Debreczeni JÉ; Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, United Kingdom.
  • Breed J; Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, United Kingdom.
  • Leopold K; Gandeeva Therapeutics, Inc., Burnaby, British Columbia V5C 6N5, Canada.
  • Patel A; Gandeeva Therapeutics, Inc., Burnaby, British Columbia V5C 6N5, Canada.
  • Jahagirdar D; Gandeeva Therapeutics, Inc., Burnaby, British Columbia V5C 6N5, Canada.
  • Lyons B; Gandeeva Therapeutics, Inc., Burnaby, British Columbia V5C 6N5, Canada.
  • Subramaniam S; Gandeeva Therapeutics, Inc., Burnaby, British Columbia V5C 6N5, Canada.
  • Phillips C; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Yeates TO; Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, United Kingdom.
Proc Natl Acad Sci U S A ; 120(37): e2305494120, 2023 09 12.
Article en En | MEDLINE | ID: mdl-37669364
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Texto completo: 1 Colección: 01-internacional Asunto principal: Diagnóstico por Imagen Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Diagnóstico por Imagen Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article