Correct and Incorrect Recommendations for or against Fine Needle Biopsies of Hypofunctioning Thyroid Nodules: Performance of Different Ultrasound-based Risk Stratification Systems.
Nuklearmedizin
; 63(1): 21-33, 2024 Feb.
Article
en En
| MEDLINE
| ID: mdl-37871628
ABSTRACT
PURPOSE:
To evaluate the recommendations for or against fine needle biopsy (FNB) of hypofunctioning thyroid nodules (TNs) using of five different Ultrasound (US) -based risk stratification systems (RSSs).METHODS:
German multicenter study with 563 TNs (≥â10âmm) in 534 patients who underwent thyroid US and surgery. All TNs were evaluated with ACR TI-RADS, EU-TIRADS, ATA, K-TIRADS 2016 and modified K-TIRADS 2021. A correct recommendation was defined as malignant TN with recommendation for FNB (appropriate) or benign TN without recommendation for FNB (avoided). An incorrect recommendation was defined as malignant TN without recommendation for FNB (missed) or benign TN with recommendation for FNB (unnecessary).RESULTS:
ACR TI-RADS demonstrated the highest rate of correct (42.3â%) and lowest rate of incorrect recommendations (57.7â%). The other RRSs showed similar results for correct (26.5â%-35.7â%) and incorrect (64.3â%-73.5â%) recommendations. ACR TI-RADS demonstrated the lowest rate of unnecessary (73.4â%) and the highest rate of appropriate (26.6â%) FNB recommendation. For other RSSs, the rates of unnecessary and appropriate FNB were between 75.2â%-77.1â% and 22.9â%-24.8â%. The lowest rate of missed FNB (14.7â%) and the highest rate of avoided FNB (85.3â%) was found for ACR TI-RADS.âFor the other RSSs, the rates of missed and avoided FNB were between 17.8â%-26.9â% and 73.1â%-82.2â%. When the size cutoff was disregarded, an increase of correct recommendations and a decrease of incorrect recommendations was observed for all RSSs.CONCLUSION:
The RSSs vary in their ability to correctly recommend for or against FNB. An understanding of the impact of nodule size cutoffs seems necessary for the future of TIRADS.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Neoplasias de la Tiroides
/
Nódulo Tiroideo
Límite:
Humans
Idioma:
En
Revista:
Nuklearmedizin
Año:
2024
Tipo del documento:
Article
País de afiliación:
Alemania