Amphiphilic polymeric nanodrug integrated with superparamagnetic iron oxide nanoparticles for synergistic antibacterial and antitumor therapy of colorectal cancer.

Li, Xiaohui; Niu, Jiazhen; Deng, Lingling; Yu, Yunjian; Zhang, Liuwei; Chen, Qixian; Zhao, Jingwen; Wang, Bangmao; Gao, Hui

Li, Xiaohui; Niu, Jiazhen; Deng, Lingling; Yu, Yunjian; Zhang, Liuwei; Chen, Qixian; Zhao, Jingwen; Wang, Bangmao; Gao, Hui.

Afiliación

Li X; State Key Laboratory of Separation Membranes and Membrane Processes, School of Materials Science and Engineering, Tiangong University, Tianjin 300387, China.
Niu J; State Key Laboratory of Separation Membranes and Membrane Processes, School of Materials Science and Engineering, Tiangong University, Tianjin 300387, China.
Deng L; School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin 300384, China.
Yu Y; State Key Laboratory of Separation Membranes and Membrane Processes, School of Materials Science and Engineering, Tiangong University, Tianjin 300387, China.
Zhang L; Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing, Zhejiang 314100, China.
Chen Q; Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing, Zhejiang 314100, China.
Zhao J; Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin 300052, China.
Wang B; Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin 300052, China.
Gao H; State Key Laboratory of Separation Membranes and Membrane Processes, School of Materials Science and Engineering, Tiangong University, Tianjin 300387, China. Electronic address: huigao@tiangong.edu.cn.

Acta Biomater ; 173: 432-441, 2024 Jan 01.

Article en En | MEDLINE | ID: mdl-37984629

Asunto(s)

Antiinfecciosos; Neoplasias Colorrectales; Profármacos; Humanos; Especies Reactivas de Oxígeno; Ácido Oléico; Platino (Metal); Fusobacterium nucleatum; Neoplasias Colorrectales/tratamiento farmacológico; Neoplasias Colorrectales/patología; Polímeros; Nanopartículas Magnéticas de Óxido de Hierro; Antibacterianos/farmacología; Peroxidasas; Línea Celular Tumoral; Microambiente Tumoral

Palabras clave

Chemotherapy; Colorectal cancer; Ferroptosis; Fusobacterium nucleatum; Nanodrug

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Texto completo: 1 Colección: 01-internacional Asunto principal: Profármacos / Neoplasias Colorrectales / Antiinfecciosos Límite: Humans Idioma: En Revista: Acta Biomater Año: 2024 Tipo del documento: Article País de afiliación: China

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