Dose-averaged LET optimized carbon-ion radiotherapy for head and neck cancers.

Koto, Masashi; Ikawa, Hiroaki; Inaniwa, Taku; Imai, Reiko; Shinoto, Makoto; Takiyama, Hirotoshi; Isozaki, Tetsuro; Mizuno, Hideyuki; Kohno, Ryosuke; Takahashi, Ikumi; Yoshida, Naoki; Yamada, Shigeru

Koto, Masashi; Ikawa, Hiroaki; Inaniwa, Taku; Imai, Reiko; Shinoto, Makoto; Takiyama, Hirotoshi; Isozaki, Tetsuro; Mizuno, Hideyuki; Kohno, Ryosuke; Takahashi, Ikumi; Yoshida, Naoki; Yamada, Shigeru.

Afiliación

Koto M; QST Hospital, National Institutes for Quantum Science and Technology, Chiba, Japan. Electronic address: koto.masashi@qst.go.jp.
Ikawa H; QST Hospital, National Institutes for Quantum Science and Technology, Chiba, Japan.
Inaniwa T; Department of Accelerator and Medical Physics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba, Japan.
Imai R; QST Hospital, National Institutes for Quantum Science and Technology, Chiba, Japan.
Shinoto M; QST Hospital, National Institutes for Quantum Science and Technology, Chiba, Japan.
Takiyama H; QST Hospital, National Institutes for Quantum Science and Technology, Chiba, Japan.
Isozaki T; QST Hospital, National Institutes for Quantum Science and Technology, Chiba, Japan.
Mizuno H; Department of Accelerator and Medical Physics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba, Japan.
Kohno R; Department of Radiologic Sciences, Graduate School of Health and Welfare Sciences, International University of Health and Welfare, Tokyo, Japan.
Takahashi I; Accelerator Engineering Corporation, Chiba, Japan.
Yoshida N; Accelerator Engineering Corporation, Chiba, Japan.
Yamada S; QST Hospital, National Institutes for Quantum Science and Technology, Chiba, Japan.

Radiother Oncol ; 194: 110180, 2024 May.

Article en En | MEDLINE | ID: mdl-38403023

ABSTRACT

ABSTRACT

This feasibility study confirmed the initial safety and efficacy of a novel carbon-ion radiotherapy (CIRT) using linear energy transfer (LET) painting for head and neck cancer. This study is the first step toward establishing CIRT with LET painting in clinical practice and making it a standard practice in the future.

Asunto(s)

Estudios de Factibilidad; Neoplasias de Cabeza y Cuello; Radioterapia de Iones Pesados; Transferencia Lineal de Energía; Dosificación Radioterapéutica; Humanos; Neoplasias de Cabeza y Cuello/radioterapia; Radioterapia de Iones Pesados/métodos; Masculino; Femenino; Anciano; Persona de Mediana Edad

Palabras clave

Carbon-ion radiotherapy; Dose-averaged LET; Head and neck cancer; LET optimization; LET painting

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Texto completo: 1 Colección: 01-internacional Asunto principal: Dosificación Radioterapéutica / Estudios de Factibilidad / Transferencia Lineal de Energía / Radioterapia de Iones Pesados / Neoplasias de Cabeza y Cuello Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Radiother Oncol Año: 2024 Tipo del documento: Article

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