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Neuropsychological and biopsychosocial evolution, therapeutic adherence and unmet care needs during paediatric transplantation: study protocol of a mixed-methods design (observational cohort study and focus groups) - the TransplantKIDS mental health project.
Garrido-Bolton, Jessica; Alcamí-Pertejo, Margarita; de la Vega, Rocío; Hernández-Oliveros, Francisco; Pérez-Martínez, Antonio; Bravo-Ortiz, María Fe; Fernández-Jiménez, Eduardo.
Afiliación
  • Garrido-Bolton J; Department of Psychiatry, Clinical Psychology and Mental Health, La Paz University Hospital, Madrid, Spain.
  • Alcamí-Pertejo M; Department of Psychiatry, Clinical Psychology and Mental Health, La Paz University Hospital, Madrid, Spain.
  • de la Vega R; Department of Personality, Evaluation and Psychological Treatment, University of Málaga, Málaga, Spain.
  • Hernández-Oliveros F; Instituto Biomédico de Málaga - IBIMA Plataforma Bionand, Málaga, Spain.
  • Pérez-Martínez A; Department of Pediatric Surgery, La Paz University Hospital, Madrid, Spain.
  • Bravo-Ortiz MF; Department of Pediatric Hemato-Oncology, La Paz University Hospital, Madrid, Spain.
  • Fernández-Jiménez E; Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.
Front Psychol ; 15: 1308418, 2024.
Article en En | MEDLINE | ID: mdl-38449767
ABSTRACT
The present article describes the protocol of a mixed-methods study (an observational cohort design and focus groups), aimed to examine neuropsychological functioning and other biopsychosocial outcomes, therapeutic adherence and unmet care needs in paediatric population undergoing solid organ or allogeneic hematopoietic transplant during the pre- and post-transplant phases. Following a multi-method/multi-source approach, neuropsychological domains will be comprehensively measured with objective tests (SDMT, K-CPT 2/CPT 3, TAVECI/TAVEC, WISC-V/WAIS-IV Vocabulary and Digit Span subtests, Verbal Fluency tests, Stroop, ROCF, and TONI-4); ecological executive functioning, affective and behavioral domains, pain intensity/interference, sleep quality and therapeutic adherence will be assessed through questionnaires (parent/legal guardians-reported BRIEF-2 and BASC-3; and self-reported BASC-3, BPI, PROMIS, AIQ and SMAQ); and blood levels of prescribed drugs will be taken from each patient's medical history. These outcomes will be measured at pre-transplant and at 4-weeks and 6-months post-transplant phases. The estimated sample size was 60 patients (any type of transplant, solid organ, or hematopoietic) from La Paz University Hospital (Madrid, Spain). Finally, three focus group sessions will be organized with patients, parents/guardians, and transplant clinicians (n = 15, with 5 participants per group), in order to qualitatively identify unmet care needs during the pre-, and post-transplant stages of the process. The study protocol was registered at ClinicalTrials.gov (NCT05441436).
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Texto completo: 1 Colección: 01-internacional Idioma: En Revista: Front Psychol Año: 2024 Tipo del documento: Article País de afiliación: España

Texto completo: 1 Colección: 01-internacional Idioma: En Revista: Front Psychol Año: 2024 Tipo del documento: Article País de afiliación: España