Determination of the levels and possible associations of alpha2-macroglobulin with autoantibodies in the serum of patients with various forms of autoimmune thyroiditis.
Biomed Khim
; 70(2): 125-129, 2024 Apr.
Article
en En
| MEDLINE
| ID: mdl-38711412
ABSTRACT
Antibodies to thyroid peroxidase (AB-TPO), antibodies to thyroglobulin (AB-TG), and the content of α2-macroglobulin (α2-MG) have been studied in serum samples of patients with autoimmune thyroiditis (AIT). All the patients were divided into 3 groups depending on age 25-35, 36-50, 51-65 years. We found a significant change in the thyroid panel parameters in AIT, but without significant changes in the average concentration of α2-MG in the age groups of patients. This may be due to the accumulation and retention of complexes of defective forms of α2-MG in the circulation associated with their decreased ability to bind to receptors.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Autoanticuerpos
/
Tiroiditis Autoinmune
/
Alfa-Macroglobulinas
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Biomed Khim
Año:
2024
Tipo del documento:
Article
País de afiliación:
Azerbaiyán