Tissue characterization using axicon probe-assisted common-path optical coherence tomography.
Opt Express
; 32(11): 20194-20206, 2024 May 20.
Article
en En
| MEDLINE
| ID: mdl-38859135
ABSTRACT
In this work, a common-path optical coherence tomography (OCT) system is demonstrated for characterizing the tissue in terms of some optical properties. A negative axicon structure chemically etched inside the fiber tip is employed as optical probe in the OCT. This probe generates a quality Bessel beam owning a large depth-of-field, â¼700 µm and small central spot size, â¼3 µm. The OCT system is probing the sample without using any microscopic lens. For experimental validation, the OCT imaging of chicken tissue has been obtained along with estimation of its refractive index and optical attenuation coefficient. Afterwards, the cancerous tissue is differentiated from the normal tissue based on the OCT imaging, refractive index, and optical attenuation coefficient. The respective tissue samples are collected from the human liver and pancreas. This probe could be a useful tool for endoscopic or minimal-invasive inspection of malignancy inside the tissue either at early-stage or during surgery.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Pollos
/
Tomografía de Coherencia Óptica
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Opt Express
Asunto de la revista:
OFTALMOLOGIA
Año:
2024
Tipo del documento:
Article