Palliative radiotherapy: New prognostic factors for patients with bone metastasis.
Cancer Radiother
; 28(3): 236-241, 2024 Jun.
Article
en En
| MEDLINE
| ID: mdl-38871605
ABSTRACT
PURPOSE:
Many cancer patients develop bone metastases, however the prognosis of overall survival differs. To provide an optimal treatment for these patients, especially towards the end of life, a reliable prediction of survival is needed. The goal of this study was to find new clinical factors in relation to overall survival. MATERIALS ANDMETHODS:
Prospectively 22 clinical factors were collected from 734 patients. The Kaplan-Meier and Cox regression models were used.RESULTS:
Most patients were diagnosed with lung cancer (29%), followed by prostate (19.8%) and breast cancer (14.7%). Median overall survival was 6.4months. Fourteen clinical factors showed significance in the univariate analyses. In the multivariate analyses 6 factors were found to be significant for the overall survival Karnofsky performance status, primary tumor, gender, total organs affected, morphine use and systemic treatment options after radiotherapy.CONCLUSION:
Morphine use and systemic treatment options after radiotherapy, Karnofsky performance status, primary tumor, gender and total organs affected are strong prediction factors on overall survival after palliative radiotherapy in patients with bone metastasis. These factors are easily applicable in the clinic.Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Cuidados Paliativos
/
Neoplasias Óseas
/
Estado de Ejecución de Karnofsky
Límite:
Adult
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Aged
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Aged80
/
Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Cancer Radiother
Asunto de la revista:
NEOPLASIAS
/
RADIOTERAPIA
Año:
2024
Tipo del documento:
Article