Consensus guidelines for the management of adult low-grade gliomas for low and middle-income countries.
J Pak Med Assoc
; 74(3 (Supple-3)): S93-S99, 2024 Mar.
Article
en En
| MEDLINE
| ID: mdl-39262069
ABSTRACT
Low-grade gliomas (LGG) are brain tumors of glial cells origin. They are grade 1 and grade 2 tumors according to the WHO classification. Diagnosis of LGG is made through imaging, histopathological analysis, and use of molecular markers. Imaging alone does not establish the grade of the tumor and thus a histopathological examination of tissue is crucial in establishing the definite histopathological diagnosis. Clinical presentation varies according to the location and size of the tumor. Surgical resection is strongly recommended in LGG over observation to improve overall survival as surgery leads to greater benefit due to progression-free survival. Radiation has shown benefits in LGG patients in randomized controlled trials and chemotherapy with temozolomide has also shown good results. This paper covers the principles of low-grade gliomas management and summarizes the recommendations for the LMICs.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Neoplasias Encefálicas
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Países en Desarrollo
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Glioma
Límite:
Adult
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Humans
Idioma:
En
Revista:
J Pak Med Assoc
/
J. Pak. Med. Assoc
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Journal of the Pakistan Medical Association
Año:
2024
Tipo del documento:
Article
País de afiliación:
Pakistán