Purification and characterization of the U-particle, a cellular constituent whose synthesis is stimulated by Mengovirus infection.
Arch Virol Suppl
; 9: 299-306, 1994.
Article
en En
| MEDLINE
| ID: mdl-8032261
ABSTRACT
We have isolated a cellular protein particle whose synthesis is induced by infection with Mengovirus or TMEV. The U-particle inhibits translation in vitro and binds to both capped and uncapped mRNA's. It is spherical, 12 nm in diameter, and is composed of multiple copies of two polypeptide subunits having molecular weights of 23,000 and 25,000 which do not appear to be glycosylated or phosphorylated. U-particles are capable of inhibiting mRNA translation in vitro.
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Colección:
01-internacional
Asunto principal:
Proteínas de Unión al ARN
/
Mengovirus
/
Cuerpos de Inclusión Viral
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Arch Virol Suppl
Asunto de la revista:
VIROLOGIA
Año:
1994
Tipo del documento:
Article
País de afiliación:
Canadá