Occupational exposure to antineoplastic agents and parameters for renal dysfunction.
Int Arch Occup Environ Health
; 69(3): 215-8, 1997.
Article
en En
| MEDLINE
| ID: mdl-9049673
ABSTRACT
To study the nephrotoxic effects of occupational exposure to antineoplastic agents, the early renal effect parameters retinol-binding protein (RBP) and albumin (ALB) were determined in the urine of 11 hospital workers involved in the preparation and administration of antineoplastic agents and in 23 hospital workers not involved in drug handling, who served as nonexposed controls. No significant difference was found between the exposed group and the nonexposed control group with respect to the early renal effect parameters RBP and ALB. Although it was demonstrated that the hospital workers were exposed to cyclophosphamide (CP) and probably other antineoplastic agents, the results of the present study show that these exposure levels did not cause nephrotoxic effects.
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Colección:
01-internacional
Asunto principal:
Exposición Profesional
/
Riñón
/
Antineoplásicos
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Int Arch Occup Environ Health
Año:
1997
Tipo del documento:
Article
País de afiliación:
Países Bajos