Complementary value of five carcinoma markers for the diagnosis of malignant mesothelioma, adenocarcinoma metastasis, and reactive mesothelium in serous effusions.
Diagn Cytopathol
; 17(2): 115-20, 1997 Aug.
Article
en En
| MEDLINE
| ID: mdl-9258618
ABSTRACT
Cytological slides of serous fluids of 41 malignant mesotheliomas, 88 metastatic adenocarcinomas, and 25 reactive effusions were immunostained with the antibodies anti-CEA, MOC-31, Leu-M1, Ber-EP4, and B72.3. Most mesotheliomas and all reactive fluids failed to stain with these antibodies. The sensitivity of the five markers to detect carcinoma cells differed remarkably. Especially MOC-31, Ber-EP4, and B72.3 stained with a high number of carcinoma cases and the complemetary value of Ber-EP4 and B72.3 to immunostain carcinoma cells was impressive 94% of the metastatic adenocarcinoma cases reacted with Ber-EP4 or B72.3 in contrast to 1 of 41 malignant mesotheliomas.
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Colección:
01-internacional
Asunto principal:
Neoplasias Peritoneales
/
Derrame Pleural
/
Neoplasias Pleurales
/
Adenocarcinoma
/
Biomarcadores de Tumor
/
Mesotelioma
/
Anticuerpos Antineoplásicos
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Diagn Cytopathol
Asunto de la revista:
PATOLOGIA
Año:
1997
Tipo del documento:
Article
País de afiliación:
Países Bajos