Trioxane dimers have potent antimalarial, antiproliferative and antitumor activities in vitro.
Bioorg Med Chem
; 5(7): 1257-65, 1997 Jul.
Article
en En
| MEDLINE
| ID: mdl-9377085
ABSTRACT
A series of tetracyclic and tricyclic trioxane dimers has been prepared with ether and ester tethers of varying length and flexibility. Several of these trioxane dimers have been found to have potent and potentially therapeutically valuable antimalarial, antiproliferative, and antitumor activities in vitro.
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Colección:
01-internacional
Asunto principal:
Compuestos Heterocíclicos
/
Antimaláricos
/
Antineoplásicos
Límite:
Humans
Idioma:
En
Revista:
Bioorg Med Chem
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
1997
Tipo del documento:
Article
País de afiliación:
Estados Unidos