POEMS syndrome with vascular lesions and renal carcinoma - possible role of cytokines.
Eur J Med Res
; 3(6): 304-6, 1998 Jun 17.
Article
en En
| MEDLINE
| ID: mdl-9620893
ABSTRACT
We describe here the case of a 60 years man with POEMS syndrome associated with renal tumor and vascular lesions. The patient had osteosclerotic myeloma IgA-lambda, polyneuropathy, endocrinopathy and skin changes. In addition, he developed renal clear cell carcinoma and gangrena of lower limbs. The humoral study showed thrombocytosis, high levels of IL-1beta and IL-6 and of some coagulative/fibrinolytic and endothelial factors (von Willebrand factor, plasmin-antiplasmine complexes, plasminogen activator). We suggest the hypothesis that these factors are capable of determining some manifestations of POEMS syndrome.
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Colección:
01-internacional
Asunto principal:
Vasculitis
/
Citocinas
/
Síndrome POEMS
/
Adenocarcinoma de Células Claras
/
Neoplasias Renales
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Eur J Med Res
Asunto de la revista:
MEDICINA
Año:
1998
Tipo del documento:
Article
País de afiliación:
Italia