Association of quality of life and disease control with cigarette smoking in patients with severe asthma
Braz. j. med. biol. res
; 55: e11149, 2022. tab, graf
Artigo
em Inglês
|
LILACS-Express
| LILACS
| ID: biblio-1355921
Biblioteca responsável:
BR1.1
ABSTRACT
More information is needed on asthma control and health-related quality of life (HRQoL) in smokers with severe asthma. The main study objective was to characterize the association of HRQoL and disease control with cigarette smoking in individuals with severe asthma. A secondary objective was to analyze subject characteristics according to asthma onset asthma that developed before smoking initiation versus asthma that developed after smoking initiation. This cross-sectional study included subjects with severe asthma aged 18-65 years. HRQoL was assessed using the Asthma Quality of Life Questionnaire (AQLQ) and asthma control was assessed using the Asthma Control Test (ACT) and Global Initiative for Asthma (GINA) criteria. Of the 87 patients studied, 58 (66.7%) were classified as asthmatics who had never smoked and 29 (33.3%) as asthmatics with smoking exposure. The proportion of subjects with uncontrolled asthma was higher in the asthma and smoking group (GINA criteria P=0.032 and ACT criteria P=0.003. There were no between-group differences in overall AQLQ score (P=0.475) or AQLQ domain scores (P>0.05). Fifty-eight subjects (66.7%) were nonsmokers, 20 (23%) had asthma onset before smoking, and 9 (10.3%) had asthma onset after smoking. Asthma onset before smoking was associated with uncontrolled asthma (P=0.013). In subjects with severe asthma, smoking was associated with a higher rate of uncontrolled disease but not with HRQoL scores.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Temas:
Geral
Base de dados:
LILACS
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Fundação Hospitalar Getúlio Vargas/BR
/
Hospital das Clínicas de Porto Alegre/BR
/
Universidade Federal do Rio Grande do Sul/BR
/
Universidade Federal do Rio Grande do Sul, Serviço de Pneumologia, Hospital das Clínicas de Porto Alegre/BR
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