Effect of weekly versus daily primaquine on Plasmodium vivax malaria recurrences: A real-life cohort study
Rev. Soc. Bras. Med. Trop
; 55: e0738, 2022. tab, graf
Artigo
em Inglês
|
LILACS-Express
| LILACS
| ID: biblio-1376352
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT Background:
Although primaquine (PQ) is indicated for G6PD-deficient patients, data on weekly PQ use in Brazil are limited.Methods:
We aimed to investigate malaria recurrences among participants receiving daily and weekly PQ treatments in a real-life setting of two municipalities in the Amazon between 2019 and 2020.Results:
Patients receiving weekly PQ treatment had a lower risk of recurrence than those receiving daily PQ treatment (risk ratio 0.62, 95% confidence interval 0.41-0.94), using a model adjusted for study site.Conclusions:
Weekly PQ use did not increase the risk of malaria recurrence. Further studies with larger populations are warranted.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2022
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Brasil
Instituição/País de afiliação:
Fundação de Medicina Tropical Doutor Heitor Vieira Dourado/BR
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