Melanoma nodular: um subtipo agressivo / Nodular melanoma: an agressive subtype

ABSTRACT

Malignant melanoma is considered the most aggressive skin cancer due to its rapid evolution and risk of metastasizing. Early diagnosis and treatment can save the patient's life, and the biological factors of each melanoma subtype must be studied for better patient management. Currently, it is known that nodular subtype melanoma is the most aggressive due to its rapid vertical evolution, with a minor epidermal component but an important dermal component, which increases the risk of lymph node and hematogenous metastasis. Clinical, histopathological, dermoscopic and biological characteristics can help with the diagnosis and subsequent treatment of these patients