Exercise training improves quality of life in women with subclinical hypothyroidism: a randomized clinical trial
Arch. endocrinol. metab. (Online)
; 62(5): 530-536, Oct. 2018. tab
Article
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| LILACS
| ID: biblio-983789
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT Objective:
The aim was to evaluate the quality of life (HRQoL) in women with subclinical hypothyroidism (sHT) after 16 weeks of endurance training. Subjects andmethods:
In the first phase, a cross-sectional study was conducted in which 22 women with sHT (median age 41.5 (interquartile range 175) years, body mass index 26.2 (8.7) kg/m2, thyroid stimulating hormone > 4.94 mIU/L and free thyroxine between 0.8 and 1.3 ng/dL were compared to a group of 33 euthyroid women concerned to HRQoL. In the second phase, a randomized clinical trial was conducted where only women with sHT were randomly divided into two groups sHT-Tr (n = 10) - participants that performed an exercise program - and sHT-Sed (n = 10) - controls. Exercise training consisted of 60 minutes of aerobic activities (bike and treadmill), three times a week, for 16 weeks. The HRQoL was assessed by the SF-36 questionnaire in the early and at the end of four months.Results:
Women with sHT had lower scores on functional capacity domain in relation to the euthyroid ones (770 ± 23.0 vs. 88.8 ± 14.6; p = 0.020). The sHT-Tr group improved functional capacity, general health, emotional aspects, mental and physical component of HRQoL after training period, while the sHT-Sed group showed no significant changes.Conclusion:
After 16 weeks of aerobic exercise training, there were remarkable improvements in HRQoL in women with sHT.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Qualidade de Vida
/
Exercício Físico
/
Terapia por Exercício
/
Hipotireoidismo
Tipo de estudo:
Clinical_trials
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Arch. endocrinol. metab. (Online)
Assunto da revista:
ENDOCRINOLOGIA
/
METABOLISMO
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Brasil