Persistent polyclonal B lymphocytosis: morphological, immunological, cytogenetic and molecular analysis of an Italian case.
Leuk Res
; 24(10): 877-9, 2000 Oct.
Article
em En
| MEDLINE
| ID: mdl-10996207
ABSTRACT
We describe a case of persistent polyclonal B-cell lymphocytosis (PPBL) studied by morphological, immunological, cytogenetic and molecular analysis. PPBL is a rare lymphoproliferative disorder with an unclear natural history. Although a few cases of malignancies are observed during PPBL, this disorder is usually considered to be an indolent syndrome. A longer follow-up in a larger number of patients is needed in order to clarify the natural history of PPBL and its potential to transform into a malignancy. As PPBL is a rare disease, establishing an international PPBL registry could be the most effective way to understand the natural history of this disease and to discover its etiologic factors.
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Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Linfócitos B
/
Aberrações Cromossômicas
/
Linfocitose
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Leuk Res
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Itália