Interleukin 18 (IL-18) levels in patients with sepsis.

Endo, S; Inada, K; Yamada, Y; Wakabayashi, G; Ishikura, H; Tanaka, T; Sato, S

Endo, S; Inada, K; Yamada, Y; Wakabayashi, G; Ishikura, H; Tanaka, T; Sato, S.

Afiliação

Endo S; Critical Care and Emergency Center, Iwate Medical University, Morioka, Japan.

J Med ; 31(1-2): 15-20, 2000.

Article em En | MEDLINE | ID: mdl-10998752

RESUMO

IL-18 levels in the blood of 13 sepsis patients were assessed. The IL-18 values were significantly correlated with their Acute Physiology and Chronic Health Evaluation (APACHE) II scores, and they were a good reflection of the severity of the disease. There was also a strong correlation between the IL-18 values and the patients' inflammatory cytokine levels. The results suggested strong involvement of IL-18 in the pathogenesis of sepsis.

Assuntos

Interleucina-18/sangue; Sepse/sangue; APACHE; Queimaduras/patologia; Feminino; Humanos; Interleucina-6/sangue; Interleucina-8/sangue; Masculino; Sepse/diagnóstico; Sepse/mortalidade; Fatores de Tempo; Fator de Necrose Tumoral alfa/metabolismo

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Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Sepse / Interleucina-18 Tipo de estudo: Diagnostic_studies Limite: Female / Humans / Male Idioma: En Revista: J Med Ano de publicação: 2000 Tipo de documento: Article País de afiliação: Japão

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