Hematopoietic progenitor cell counts performed by the Sysmex SE-9000 analyzer can guide timing of peripheral blood stem cell harvest.
Anticancer Res
; 21(1B): 601-4, 2001.
Article
em En
| MEDLINE
| ID: mdl-11299812
ABSTRACT
BACKGROUND:
We studied whether the hematopoietic progenitor cell (HPC) count in peripheral blood as evaluated by an automated counter, the Sysmex SE-9000, correlated with CD34 positive (+) cell count and therefore could guide the timing of peripheral blood stem cell (PBSC) harvest. MATERIALS ANDMETHODS:
HPC count and flow cytometric CD34+ cell count were measured in 90 peripheral blood samples and 30PBSC samples. The correlation between HPC count and apheretic CD34+ cell yield was examined in 19 patients.RESULTS:
HPC count showed good correlations with CD34+ cell count in peripheral blood (r = 0.699) and PBSC (r = 0.892). The correlation between peripheral blood HPC count and apheretic CD34+ cell yield also was good (r = 0.789).CONCLUSION:
Automated HPC counting can be used as a screening test to guide the timing of PBSC harvest.
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Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Contagem de Células Sanguíneas
/
Remoção de Componentes Sanguíneos
/
Células-Tronco Hematopoéticas
Tipo de estudo:
Evaluation_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Anticancer Res
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Japão