Natural paratuberculosis infection in rabbits in Scotland.
J Comp Pathol
; 124(4): 290-9, 2001 May.
Article
em En
| MEDLINE
| ID: mdl-11437505
ABSTRACT
Natural paratuberculosis infection of rabbits (Oryctolagus cuniculus) was recently diagnosed in Scotland, and an investigation into the pathology of the disease in wild rabbits is reported in this paper. Evidence of Mycobacterium avium subsp. paratuberculosis (M.a. paratuberculosis) infection was detected in 22% of 110 rabbits; the organism was cultured from 17 of 110 rabbits, and histopathological lesions consistent with M.a. paratuberculosis infection were noted in 18 of 98 rabbits examined. No macroscopical lesions suggestive of M.a. paratuberculosis infection were observed. The histopathological lesions were either severe or mild. Severe lesions consisted of extensive macrophage granulomata and numerous giant cells, with many intracellular acid-fast bacteria in the small intestine. For the examination of formalin-fixed, paraffin wax-embedded tissues, neither immunohistochemistry nor the polymerase chain reaction was as sensitive a method of diagnosis as histopathology.
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Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Paratuberculose
/
Coelhos
/
Mycobacterium avium subsp. paratuberculosis
/
Animais Selvagens
Limite:
Animals
País/Região como assunto:
Europa
Idioma:
En
Revista:
J Comp Pathol
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Reino Unido