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Streptococcus agalactiae infective endocarditis: analysis of 30 cases and review of the literature, 1962-1998.
Sambola, A; Miro, J M; Tornos, M P; Almirante, B; Moreno-Torrico, A; Gurgui, M; Martinez, E; Del Rio, A; Azqueta, M; Marco, F; Gatell, J M.
Afiliação
  • Sambola A; Hospital Clinic-Institut d'Investigacions Biomediques August Pi i Sunyer, University of Barcelona, E-08036-Barcelona, Spain.
Clin Infect Dis ; 34(12): 1576-84, 2002 Jun 15.
Article em En | MEDLINE | ID: mdl-12032892
We describe 30 cases (1.7%) of community-acquired penicillin-susceptible Streptococcus agalactiae endocarditis among 1771 episodes of endocarditis diagnosed in 4 Spanish hospitals from 1975 through 1998. Endocarditis affected a native valve (most often the mitral valve) in 25 cases (83%). Surgical valve replacement was performed for 12 patients (40%). Fourteen patients (47%) died. Mortality rates for patients with native and prosthetic valve endocarditis were 36% and 100%, respectively (P=.01). The mortality rate for native valve endocarditis decreased during the last 6 years of the study (from 61% in 1975-1992 to 8% in 1993-1998; P<.05). Additionally, 115 cases in the literature from 1962-1998 were reviewed. During 1980-1998, the percentage of patients who underwent cardiac surgery increased from 24% (in the previous period, 1962-1979) to 43% (P=.05) and the mortality rate decreased from 45% to 34% (P=NS). S. agalactiae is an uncommon cause of endocarditis with a high mortality rate, although the prognosis of native valve endocarditis has improved in recent years, probably because of an increased use of cardiac surgery.
Assuntos
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Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Streptococcus agalactiae / Endocardite Bacteriana Tipo de estudo: Incidence_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2002 Tipo de documento: Article País de afiliação: Espanha
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Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Streptococcus agalactiae / Endocardite Bacteriana Tipo de estudo: Incidence_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2002 Tipo de documento: Article País de afiliação: Espanha