Severe lactic acidosis and thiamine deficiency during total parenteral nutrition--case report.
Hepatogastroenterology
; 51(55): 253-5, 2004.
Article
em En
| MEDLINE
| ID: mdl-15011878
ABSTRACT
We encountered a case of total parenteral nutrition-associated lactic acidosis that did not respond to sodium bicarbonate or other conventional emergency treatments. He was characterized by minimal food intake before surgery, delayed gastric emptying after pylorus-preserving pancreatoduodenectomy due to pancreas head cancer and long-term total parenteral nutrition without food intake and vitamin supplements after surgery. After thiamine administration, the patient very quickly recovered with dramatic reestablishment of the acid-base balance. We emphasize the need to supplement total parenteral nutrition with thiamine-containing vitamins for the patients whose food intake does not meet nutritional requirements and to intravenously replenish using high-dose thiamine simultaneously with the manifestation of signs and symptoms of severe lactic acidosis with unknown cause. In conclusion, thiamine deficiency should be included in the differential diagnosis of lactic acidosis for the patients who received total parenteral nutrition without food intake and vitamin supplements.
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Coleções:
01-internacional
Temas:
Geral
/
Prevencao_e_fatores_de_risco
/
Alimentacao
Base de dados:
MEDLINE
Assunto principal:
Deficiência de Tiamina
/
Acidose Láctica
/
Nutrição Parenteral Total
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
Idioma:
En
Revista:
Hepatogastroenterology
Ano de publicação:
2004
Tipo de documento:
Article