Perfusion imaging of the brain using Z-score and dynamic images obtained by subtracting images from before and after contrast injection.
Korean J Radiol
; 5(3): 143-8, 2004.
Article
em En
| MEDLINE
| ID: mdl-15467410
ABSTRACT
OBJECTIVE:
The aim of this study was to examine the feasibility of perfusion imaging of the brain using the Z-score and subtraction dynamic images obtained from susceptibility contrast MR images. MATERIALS ANDMETHODS:
Five patients, each with a normal MRI, Moya-moya, a middle cerebral artery occlusion, post-trauma syndrome, and a metastatic brain tumor, were selected for a presentation. A susceptibility-contrast echo-planar image after a routine MRI was taken as the source image with a rapid manual injection of 0.1 mmol/kg of Gd-DTPA. The inflow and washout patterns were observed from the time-signal intensity curve of the serial scans using the standard program of an MRI machine. The repeated Z-score images of the peak and late phases were made using the threshold Z-score values between 1.4 and 2.0 in four to five studies of the pre-contrast, peak, and late phases. Dynamic subtraction images were produced by subtracting sequential post-contrast images from a pre-contrast image and coloring these images using a pseudocolor mapping method.RESULTS:
In the diseases with perfusion abnormalities, the Z-score images revealed information about the degree of perfusion during the peak and late phases. However, the quality varied with the Z-score threshold and the studies selected in a group. The dynamic subtraction images were of sufficient quality with no background noise and more clearly illustrated the temporal changes in perfusion and delayed perfusion.CONCLUSION:
The Z-scores and dynamic subtraction images illustrated the degree of perfusion and sequential changes in the pattern of perfusion, respectively. These images can be used as a new complimentary method for observing the perfusion patterns in brain diseases.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
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Técnica de Subtração
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Angiografia por Ressonância Magnética
Limite:
Adult
/
Child
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Korean J Radiol
Assunto da revista:
RADIOLOGIA
Ano de publicação:
2004
Tipo de documento:
Article