Hormonology: a genomic perspective on hormonal research.
J Endocrinol
; 187(3): 333-8, 2005 Dec.
Article
em En
| MEDLINE
| ID: mdl-16423812
ABSTRACT
Recent advances in comparative genomics allow a new paradigm for hormonal research. At the centennial of the first use of the term hormone by Ernest Starling, we reflected on the changing approaches in elucidating hormonal signaling mechanisms and highlighted the inadequacy of the term endocrinology, implying remote activation, to describe the diverse modes of hormone actions. Several examples were presented to underscore the power of comparative genomics in the identification of new polypeptide hormones, receptors, and signaling pathways. We propose the use of the term hormonology to more accurately reflect the expanding boundaries of the discipline.
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Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Genômica
/
Hormônios
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
J Endocrinol
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Estados Unidos