Comparison of caudal ketamine with or without bupivacaine in pediatric subumbilical surgery.
J Natl Med Assoc
; 99(6): 670-3, 2007 Jun.
Article
em En
| MEDLINE
| ID: mdl-17595937
ABSTRACT
In this prospective, randomized, double-blind study, we evaluated the perioperative analgesic efficacy of caudal ketamine with or without bupivacaine in 62 American Society of Anesthesiologists I-II children undergoing lower abdominal surgery. Patients were randomized into three groups, and all blocks were placed under general anesthesia. Group 1 (n=20) had caudal injection of plain 0.125% bupivacaine 1 mlkg(-1). Group 2 (n=22) received caudal ketamine 0.5 mgkg(-1) diluted with 0.9% saline using the same weight-related volumes. Group 3 (n=20) received a similar dose of ketamine mixed with 0.125% bupivacaine 1 mlkg(-1). No supplementary intraoperative analgesic was required in any of the groups. Patients in group 3 had the longest duration of analgesia compared to the other two groups. There was no significant difference in the incidence of side effects among the three groups. We conclude that ketamine can safely be used as an adjuvant to prolong the duration of caudal analgesia in this group of West African children.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Bupivacaína
/
Extremidade Inferior
/
Abdome
/
Anestesia Caudal
/
Ketamina
/
Anestésicos Locais
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Risk_factors_studies
Limite:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
País/Região como assunto:
Africa
Idioma:
En
Revista:
J Natl Med Assoc
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Estados Unidos