Your browser doesn't support javascript.
loading
Doubling of testicular cancer incidence rate over the last 20 years in southern France.
Walschaerts, Marie; Huyghe, Eric; Muller, Audrey; Bachaud, Jean-Marc; Bujan, Louis; Thonneau, Patrick.
Afiliação
  • Walschaerts M; Human Fertility Research Group (EA 3694), University Paul Sabatier-Toulouse III, INSERM, Toulouse Cedex 9, France.
Cancer Causes Control ; 19(2): 155-61, 2008 Mar.
Article em En | MEDLINE | ID: mdl-18236173
ABSTRACT
In recent decades, testicular cancer incidence has considerably increased in a majority of industrialized countries. In France, short reports suggested that the testicular cancer incidence rate has also risen, especially in north-eastern regions. In Europe, geographical variation of incidence rates has been observed in Baltic countries and a clear birth cohort effect has been revealed. This study aimed to assess temporal trends in testicular cancer incidence in southern France. We examined incidence rates over a 20-year time period in a series of 506 consecutive cases of testicular cancer recorded from 1980 to 1999 in the Midi-Pyrenees region of France. Age, calendar period, and birth cohort effects were examined simultaneously using Poisson regression models. Our analysis found a significant rise in the overall incidence rate of testicular germ cell tumors from 1.27 to 3.04 per 100,000 between 1980-1984 and 1995-1999, an annual increase of 5.70%. These results, the first obtained in a large series in southern Europe, show a twofold increase in incidence rate of testicular cancer in the Midi-Pyrenees region, which is very similar to that observed in all European countries, more or less doubling in the last 20 years. Interestingly, this major jump and the apparent testicular cancer gradient between northern and southern Europe suggest considerable geographical heterogeneity in incidence, but low geographical variation in temporal trends.
Assuntos

Texto completo: 1 Coleções: 01-internacional Temas: Epidemiologia / Incidencia / Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias Testiculares / Sistema de Registros Tipo de estudo: Incidence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Cancer Causes Control Assunto da revista: EPIDEMIOLOGIA / NEOPLASIAS Ano de publicação: 2008 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Coleções: 01-internacional Temas: Epidemiologia / Incidencia / Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias Testiculares / Sistema de Registros Tipo de estudo: Incidence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Cancer Causes Control Assunto da revista: EPIDEMIOLOGIA / NEOPLASIAS Ano de publicação: 2008 Tipo de documento: Article País de afiliação: França